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Emmanuelle Vaugier
Jane Browning / Painkiller Jane
Eric Dane
Nick
Richard Roundtree
Colonel Watts
Venus Terzo
Carla Browning
Walker Howard
Blue
Callum Keith Rennie
Mitchell
Tate Donovan
Dr. Graham Knight / Lucas Insley
Paula Brancati
Young Jane
Elicia Mackenzie
Young Carla
Martin Cummins
Sergeant Flynn
Richard Harmon
Squeak